Reassessment of the positive predictive value and specificity of Xpert MTB/RIF: a diagnostic accuracy study in the context of community-wide screening for tuberculosis.
Identifieur interne : 001843 ( Main/Exploration ); précédent : 001842; suivant : 001844Reassessment of the positive predictive value and specificity of Xpert MTB/RIF: a diagnostic accuracy study in the context of community-wide screening for tuberculosis.
Auteurs : Jennifer Ho [Australie] ; Phuong Thi Bich Nguyen [Viêt Nam] ; Thu Anh Nguyen [Viêt Nam] ; Khoa Hien Tran [Viêt Nam] ; Son Van Nguyen [Viêt Nam] ; Nhung Viet Nguyen [Viêt Nam] ; Hoa Binh Nguyen [France] ; Khanh Boi Luu [Viêt Nam] ; Greg J. Fox [Australie] ; Guy B. Marks [Australie]Source :
- The Lancet. Infectious diseases [ 1474-4457 ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Expectoration (microbiologie), Femelle, Humains, Microscopie (), Mycobacterium tuberculosis (génétique), Mycobacterium tuberculosis (isolement et purification), Mâle, Prévalence, Sensibilité et spécificité, Techniques bactériologiques (), Tests diagnostiques courants, Tuberculose pulmonaire (diagnostic), Tuberculose pulmonaire (épidémiologie), Vietnam (épidémiologie), Études transversales.
- MESH :
- diagnostic : Tuberculose pulmonaire.
- génétique : Mycobacterium tuberculosis.
- isolement et purification : Mycobacterium tuberculosis.
- microbiologie : Expectoration.
- épidémiologie : Tuberculose pulmonaire, Vietnam.
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Humains, Microscopie, Mâle, Prévalence, Sensibilité et spécificité, Techniques bactériologiques, Tests diagnostiques courants, Études transversales.
English descriptors
- KwdEn :
- Adolescent, Adult, Bacteriological Techniques (methods), Cross-Sectional Studies, Diagnostic Tests, Routine, Female, Humans, Male, Microscopy (methods), Middle Aged, Mycobacterium tuberculosis (genetics), Mycobacterium tuberculosis (isolation & purification), Prevalence, Sensitivity and Specificity, Sputum (microbiology), Tuberculosis, Pulmonary (diagnosis), Tuberculosis, Pulmonary (epidemiology), Vietnam (epidemiology).
- MESH :
- diagnosis : Tuberculosis, Pulmonary.
- epidemiology : Tuberculosis, Pulmonary, Vietnam.
- genetics : Mycobacterium tuberculosis.
- isolation & purification : Mycobacterium tuberculosis.
- methods : Bacteriological Techniques, Microscopy.
- microbiology : Sputum.
- Adolescent, Adult, Cross-Sectional Studies, Diagnostic Tests, Routine, Female, Humans, Male, Middle Aged, Prevalence, Sensitivity and Specificity.
Abstract
Community-wide screening for tuberculosis with Xpert MTB/RIF as a primary screening tool overcomes some of the limitations of conventional screening. However, concerns exist about the low positive predictive value of this test in screening settings. We did a cross-sectional assessment of this diagnostic test to directly estimate the actual positive predictive value of Xpert MTB/RIF when used in the setting of community-wide screening for tuberculosis, and to draw an inference about the specificity of the test for tuberculosis detection.
DOI: 10.1016/S1473-3099(16)30067-6
PubMed: 27289387
Affiliations:
- Australie, France, Viêt Nam
- Nouvelle-Galles du Sud, Île-de-France
- Paris, Sydney
- Université de Sydney
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Le document en format XML
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Marks</name><affiliation wicri:level="4"><nlm:affiliation>Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia; South Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Woolcock Institute of Medical Research, University of Sydney, Sydney, NSW, Australia; South Western Sydney Clinical School, University of New South Wales, Sydney, NSW</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author></analytic><series><title level="j">The Lancet. 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However, concerns exist about the low positive predictive value of this test in screening settings. We did a cross-sectional assessment of this diagnostic test to directly estimate the actual positive predictive value of Xpert MTB/RIF when used in the setting of community-wide screening for tuberculosis, and to draw an inference about the specificity of the test for tuberculosis detection.</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>Viêt Nam</li></country><region><li>Nouvelle-Galles du Sud</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Sydney</li></settlement><orgName><li>Université de Sydney</li></orgName></list><tree><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Ho, Jennifer" sort="Ho, Jennifer" uniqKey="Ho J" first="Jennifer" last="Ho">Jennifer Ho</name></region><name sortKey="Fox, Greg J" sort="Fox, Greg J" uniqKey="Fox G" first="Greg J" last="Fox">Greg J. Fox</name><name sortKey="Marks, Guy B" sort="Marks, Guy B" uniqKey="Marks G" first="Guy B" last="Marks">Guy B. Marks</name></country><country name="Viêt Nam"><noRegion><name sortKey="Nguyen, Phuong Thi Bich" sort="Nguyen, Phuong Thi Bich" uniqKey="Nguyen P" first="Phuong Thi Bich" last="Nguyen">Phuong Thi Bich Nguyen</name></noRegion><name sortKey="Luu, Khanh Boi" sort="Luu, Khanh Boi" uniqKey="Luu K" first="Khanh Boi" last="Luu">Khanh Boi Luu</name><name sortKey="Nguyen, Nhung Viet" sort="Nguyen, Nhung Viet" uniqKey="Nguyen N" first="Nhung Viet" last="Nguyen">Nhung Viet Nguyen</name><name sortKey="Nguyen, Thu Anh" sort="Nguyen, Thu Anh" uniqKey="Nguyen T" first="Thu Anh" last="Nguyen">Thu Anh Nguyen</name><name sortKey="Tran, Khoa Hien" sort="Tran, Khoa Hien" uniqKey="Tran K" first="Khoa Hien" last="Tran">Khoa Hien Tran</name><name sortKey="Van Nguyen, Son" sort="Van Nguyen, Son" uniqKey="Van Nguyen S" first="Son" last="Van Nguyen">Son Van Nguyen</name></country><country name="France"><region name="Île-de-France"><name sortKey="Nguyen, Hoa Binh" sort="Nguyen, Hoa Binh" uniqKey="Nguyen H" first="Hoa Binh" last="Nguyen">Hoa Binh Nguyen</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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